Astrazeneca/Oxford vaccine approved

[Phoenix]

In the past 24 hours I have heard quite a few medical experts talking about the efficacy of the mix and match of the various vaccines - AZ&Pfizer etc. I plead ignorance on how and if they work but I get worried when I hear qualified vari-ologists* saying; It should be effective. It probably will be good.

I would like some certainty please not should, maybe and probably.

* Collective term for them all: virologists, epidemiologists, pharmacologists and on and on.

[Taipan]

Do you know which jab you're having, or not bothered anyway?

No idea fella. I'll get what i'm given.

Mine is tomorrow and the vaccine type wasn't mentioned. As I have to go to one of the big vaccine centres rather than a local surgery it could well be Pfizer but I won't refuse the Oxford one.

My wife and I had ours at the same place, but weeks apart. She got the Pfizer and I had the AZ. I booked my 2nd jab online and its in a different place to where I had the first one.

[weeksy]

In the past 24 hours I have heard quite a few medical experts talking about the efficacy of the mix and match of the various vaccines - AZ&Pfizer etc. I plead ignorance on how and if they work but I get worried when I hear qualified vari-ologists* saying; It should be effective. It probably will be good.

I would like some certainty please not should, maybe and probably.

* Collective term for them all: virologists, epidemiologists, pharmacologists and on and on.

They don't know yet, it's not like we've been testing it for 30 years. It's quite new so very little actual data

[DefTrap]

I'm officially over covid now. Most of my nearest and dearest who are vulnerable now have been jabbed. Most of those who I don't know who are vulnerable have been offered it.

I'm just cracking on now and trying not to get fined. In all honesty my greatest limiting factor now is my missus telling me off.

[gremlin]

In the past 24 hours I have heard quite a few medical experts talking about the efficacy of the mix and match of the various vaccines - AZ&Pfizer etc. I plead ignorance on how and if they work but I get worried when I hear qualified vari-ologists* saying; It should be effective. It probably will be good.

I would like some certainty please not should, maybe and probably.

* Collective term for them all: virologists, epidemiologists, pharmacologists and on and on.

They're asking volunteers for the mix n max trial. I was going to but had the jab 3 days too late to be eligible plus you can't give blood for some time afterwards.

Google it if you fancy giving it a go.

[Mussels]

Well, I ended up with the Oxford jab. Apart from the long drive it was all a bit of a non-event, not much waiting around and the staff were all good.

[Horse]

Our local major NHS centre has started using the Modena jab.

[Yorick]

Spain has now made allowances to give us expats the jab.

Mrs Y just went down and registered. Hope it's before we go to Spain in June.

[Kneerly Down]

In the past 24 hours I have heard quite a few medical experts talking about the efficacy of the mix and match of the various vaccines - AZ&Pfizer etc.
* Collective term for them all: virologists, epidemiologists, pharmacologists and on and on.

On the Today Programme yesterday, it was (honestly) Professor Snape heading the Oxford Uni study into mixing and matching the vaccines...I'm not sure if that makes it potions or dark arts mastery?

[irie]

I'm sure all here have seen this, but they don’t want the vaccine anyway, so what's the point of doing this?

https://news.sky.com/story/covid-19-eu- ... t-12287811

The European Commission has launched legal action against AstraZeneca for not respecting a contract for the supply of COVID-19 vaccines.

And in any case ...

https://www.politico.eu/article/belgium ... documents/

Belgium was warned EU’s AstraZeneca contract lacked teeth: Documents

Belgium was cautioned ahead of time that the EU's contract with drugmaker AstraZeneca didn't include harsh consequences if the company failed to deliver coronavirus vaccines on schedule, according to an opinion the consultancy Deloitte prepared for the Belgian government.

The revelation — detailed in documents acquired through a freedom of information request from the Belgian magazine Knack and analyzed with POLITICO — shows that at least one EU country was told the EU's contract might lack teeth before it was signed. But Belgium ultimately didn't act on these warnings because the contract was already largely completed.

"We assume that there are good reasons to expect that the foreseen delivery schedule will be respected," Deloitte wrote on August 17, 2020, after assessing the EU’s contract for the Belgian government. "However, the [advance purchasing agreement] does not provide for sanctions when the delivery dates and quantities are not respected*."

... at best it looks like they're on a hiding to nothing while publicising their incompetence.

* my highlight

[weeksy]

I'm sure all here have seen this,

I very much doubt it

[cheb]

Roll up, roll up, come to the Outer Hebrides if you want your jab. They've just opened bookings for anyone over 18 years old.

I reckon in about 3 weeks time all 250 of us will have had at least the first jab.

[Hoonercat]

I'm sure all here have seen this, but they don’t want the vaccine anyway, so what's the point of doing this?

https://news.sky.com/story/covid-19-eu- ... t-12287811

The European Commission has launched legal action against AstraZeneca for not respecting a contract for the supply of COVID-19 vaccines.

And in any case ...

https://www.politico.eu/article/belgium ... documents/

Belgium was warned EU’s AstraZeneca contract lacked teeth: Documents

Belgium was cautioned ahead of time that the EU's contract with drugmaker AstraZeneca didn't include harsh consequences if the company failed to deliver coronavirus vaccines on schedule, according to an opinion the consultancy Deloitte prepared for the Belgian government.

The revelation — detailed in documents acquired through a freedom of information request from the Belgian magazine Knack and analyzed with POLITICO — shows that at least one EU country was told the EU's contract might lack teeth before it was signed. But Belgium ultimately didn't act on these warnings because the contract was already largely completed.

"We assume that there are good reasons to expect that the foreseen delivery schedule will be respected," Deloitte wrote on August 17, 2020, after assessing the EU’s contract for the Belgian government. "However, the [advance purchasing agreement] does not provide for sanctions when the delivery dates and quantities are not respected*."

... at best it looks like they're on a hiding to nothing while publicising their incompetence.

* my highlight

I'll take a wild guess that it's because you're wrong, and they do want the vaccine.

[Yorick]

Only in America

https://www.bbc.com/news/world-us-canada-56905752

[irie]

I'm sure all here have seen this,

I very much doubt it

It was in all the media including BBC News so I assumed that everyone had seen it.

https://www.bbc.co.uk/news/world-europe ... deliveries.

But the question remains, what is the point of this?

https://www.politico.eu/article/belgium ... documents/

The link even says:

"The contract even has a clause saying the Commission cannot sue AstraZeneca if it doesn't deliver on time — a clause lawyers believe the Commission will seek to invalidate in a Belgian court."

Good luck with that, but you never know of course.

[irie]

Interesting take on the widely published European requirement to vaccinate 70% of the population to achieve herd immunity. This figure is predicated on the 'original' Covid transmission rate of about 2.5

Herd immunity = (1-1/transmission rate)/vaccine efficacy

Assuming vaccine efficacy = 85% and Covid transmission rate = 2.5
then vaccination rate required for herd immunity = (1-1/2.5)/.85 = 70%
(assuming no prior immunity).

But the transmission rate of the increasingly wudespread Kent variant B117 appears to be about 60% higher, thus the transmission rate becomes 2.5 X 1.6 = 4
The vaccination rate required for herd immunity = (1-1/4)/.85 = 88%

The 70% figure is now obsolete, and the true figure is nearer to 90%

Research results from Public Health England which showed that after having had the first jab:

Those who had received the Pfizer jab were 49 per cent less likely to transmit the virus to others in their households, while transmission fell by 38 per cent for those given the AstraZeneca vaccine.

If a very approximate average of 43% is used with the above transmission rate of 4 for B117 then the new transmission rate becomes about 2.3

When plugged into the above equation herd immunity is reached at about 66%

In the UK over 34m people (which is 68% of the adult population of 50m) have had their first jab, so it's no surprise that infection rates are so very low. Another success for the strategy of administering first jabs and delaying second jabs (imo).

(This does not take into account any pre-existing immunity).

[irie]

Paris prosecutors seek involuntary manslaughter charges over AstraZeneca deaths

https://www.france24.com/en/europe/2021 ... eca-deaths

Paris prosecutors are taking on and combining into an involuntary manslaughter probe three separate investigations over deaths of three people who were given the AstraZeneca Covid-19 vaccine in France, they said Wednesday.

Better to risk getting Covid and dying, eh?

"You are 50 times more likely to get a vein blood clot crossing the Atlantic by plane than getting vaccinated with AstraZeneca. Vaccines protect us from Covid-19. Let's not give into mistrust!" Health Minister Olivier Veran said earlier this month.

Oh, perhaps not.

[DefTrap]

I had my 2nd AZ a week or so ago - no reaction whatsoever (the first one I had a headache for a day)

[Supermofo]

Got my 2nd AZ on Tuesday. Most people seem to be ok on the 2nd AZ so fingers crossed I'll be ok

[Mr. Dazzle]

Got mine booked for next week now.


Technically they haven't opened it up to my age bracket yet, they're doing so tomorrow. A friend of mine pointed out they update the back end of their website before the front though, so I could book it and get a slot which isn't fucking miles away.